Assistant Member

2025

  • Manju Chauhan, Raju Shivarathri, Ariel A Aptekmann, Anuradha Chowdhary, Karl Kuchler, Jigar V Desai, Neeraj Chauhan. The Gcn5 lysine acetyltransferase mediates cell wall remodeling, antifungal drug resistance, and virulence of Candida auris. mSphere 10(4):e00069-25 (2025). doi:10.1128/msphere.00069-25.
  • Andrew L Wishart, Joseph Pechacek, Lindsey B Rosen, Jigar V Desai, Marissa A Zarakas, Taura Webb, Stefania Pittaluga, Amir Seyedmousavi, Tobias M Hohl, Douglas B Kuhns, Steven M Holland, Michail S Lionakis. Neutralizing GM-CSF autoantibodies impair neutrophil antifungal effector function in a patient with aspergillosis. Journal of Infection:106588 (2025). doi:.
  • Jigar V Desai. mSphere of Influence: Complement activity beyond systemic circulation—implications in the context of infections. mSphere 10(3):e00531-24 (2025). doi:10.1128/msphere.00531-24.
  • Kathleen AM Mills, Frederike Westermann, Vanessa Espinosa, Eric Rosiek, Jigar V Desai, Mariano A Aufiero, Yahui Guo, Fitty L Liu, Kennedy A Mitchell, Selma Tuzlak, Donatella De Feo, Michail S Lionakis, Amariliz Rivera, Burkhard Becher, Tobias M Hohl. GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus. Science immunology 10(105):eadr0547 (2025). doi:10.1126/sciimmunol.adr0547.
  • Jigar V Desai, Michail S Lionakis. Complement and fungal diseases. Journal of Allergy and Clinical Immunology (2025). doi:10.1016/j.jaci.2025.02.003.

2024

  • Dhanya Dhanyalayam, Hariprasad Thangavel, Tabinda Sidrat, Neelam Oswal, Kezia Lizardo, Michael Mauro, Xin Zhao, Hai-Hui Xue, Jigar V Desai, Jyothi F Nagajyothi. The Influence of Body Fat Dynamics on Pulmonary Immune Responses in Murine Tuberculosis: Unraveling Sex-Specific Insights. International Journal of Molecular Sciences 25(13):6823 (2024). doi:.
  • Raju Shivarathri, Manju Chauhan, Abhishek Datta, Diprasom Das, Adela Karuli, Ariel Aptekmann, Sabrina Jenull, Karl Kuchler, Shankar Thangamani, Anuradha Chowdhary, Jigar V Desai, Neeraj Chauhan. The Candida auris Hog1 MAP kinase is essential for the colonization of murine skin and intradermal persistence. MBio 15(11):e02748-24 (2024). doi:10.1128/mbio.02748-24.
  • Jigar V Desai, Michail S Lionakis. Evaluation of murine renal phagocyte-fungal interactions using intravital confocal microscopy and flow cytometry. STAR protocols 5(1):102781 (2024). doi:.
  • Jigar V Desai, Marissa A Zarakas, Andrew L Wishart, Mark Roschewski, Mariano A Aufiero, Agnes Donkò, Gustaf Wigerblad, Neta Shlezinger, Markus Plate, Matthew R James, Jean K Lim, Gulbu Uzel, Jenna RE Bergerson, Ivan Fuss, Robert A Cramer, Luis M Franco, Emily S Clark, Wasif N Khan, Daisuke Yamanaka, Georgios Chamilos, Jamel El-Benna, Mariana J Kaplan, Louis M Staudt, Thomas L Leto, Steven M Holland, Wyndham H Wilson, Tobias M Hohl, Michail S Lionakis. BTK drives neutrophil activation for sterilizing antifungal immunity. The Journal of clinical investigation 134(12) (2024). doi:.
  • Amir Arastehfar, Farnaz Daneshnia, Hrant Hovhannisyan, Nathaly Cabrera, Macit Ilkit, Jigar V Desai, Toni Gabaldón, Erika Shor, David S Perlin. A multidimensional assessment of in-host fitness costs of drug resistance in the opportunistic fungal pathogen Candida glabrata. FEMS yeast research 24:foae035 (2024). doi:10.1093/femsyr/foae035/7900768.

2023

  • Patrick Fernandes Rodrigues, Athanasios Kouklas, Grozdan Cvijetic, Nicolas Bouladoux, Mladen Mitrovic, Jigar V Desai, Djalma S Lima-Junior, Michail S Lionakis, Yasmine Belkaid, Robert Ivanek, Roxane Tussiwand. pDC-like cells are pre-DC2 and require KLF4 to control homeostatic CD4 T cells. Science immunology 8(80):eadd4132 (2023). doi:10.1126/sciimmunol.add4132.
  • Amir Arastehfar, Farnaz Daneshnia, Hrant Hovhannisyan, Diego Fuentes, Nathaly Cabrera, Christopher Quinteros, Macit Ilkit, Nevzat Ünal, Suleyha Hilmioğlu-Polat, Kauser Jabeen, Sadaf Zaka, Jigar V Desai, Cornelia Lass-Flörl, Erika Shor, Toni Gabaldon, David S Perlin. Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness. MBio 14(5):e01180-23 (2023). doi:10.1128/mbio.01180-23.
  • Anastasiia Gainullina, Denis A Mogilenko, Li-Hao Huang, Helena Todorov, Vipin Narang, Ki-Wook Kim, Lim Sheau Yng, Andrew Kent, Baosen Jia, Kumba Seddu, Karen Krchma, Jun Wu, Karine Crozat, Elena Tomasello, Regine Dress, Peter See, Charlotte Scott, Sophie Gibbings, Geetika Bajpai, Jigar V Desai, Barbara Maier, Sébastien This, Peter Wang, Stephanie Vargas Aguilar, Lucie Poupel, Sebastien Dussaud, Tyng-An Zhou, Veronique Angeli, J Magarian Blander, Kyunghee Choi, Marc Dalod, Ivan Dzhagalov, Emmanuel L Gautier, Claudia Jakubzick, Kory Lavine, Michail S Lionakis, Helena Paidassi, Michael H Sieweke, Florent Ginhoux, Martin Guilliams, Christophe Benoist, Miriam Merad, Gwendalyn J Randolph, Alexey Sergushichev, Maxim N Artyomov. Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes. Cell reports 42(2) (2023). doi:.
  • Jigar V Desai, Michail S Lionakis. C5‐C5aR1‐mediated immune responses during fungal infection: Clinical and translational implications. Clinical and Translational Medicine 13(9):e1424 (2023). doi:.
  • Jigar V Desai, Dhaneshwar Kumar, Tilo Freiwald, Daniel Chauss, Melissa D Johnson, Michael S Abers, Julie M Steinbrink, John R Perfect, Barbara Alexander, Vasiliki Matzaraki, Brendan D Snarr, Marissa A Zarakas, Vasileios Oikonomou, Lakmali M Silva, Raju Shivarathri, Emily Beltran, Luciana Negro Demontel, Luopin Wang, Jean K Lim, Dylan Launder, Heather R Conti, Muthulekha Swamydas, Micah T McClain, Niki M Moutsopoulos, Majid Kazemian, Mihai G Netea, Vinod Kumar, Jörg Köhl, Claudia Kemper, Behdad Afzali, Michail S Lionakis. C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection. Cell 186(13):2802-2822. e22 (2023). doi:.

2022

  • Jigar Desai, Christopher Francis, Kenneth Longo, Andrew Hoss. Predicting exon criticality from protein sequence. Nucleic Acids Research 50(6):3128-3141 (2022). doi:.
  • Rebecca A Drummond, Jigar V Desai, Emily E Ricotta, Muthulekha Swamydas, Clay Deming, Sean Conlan, Mariam Quinones, Veronika Matei-Rascu, Lozan Sheriff, David Lecky, Chyi-Chia R Lee, Nathaniel M Green, Nicholas Collins, Adrian M Zelazny, D Rebecca Prevots, David Bending, David Withers, Yasmine Belkaid, Julia A Segre, Michail S Lionakis. Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria. Cell host & microbe 30(7):1020-1033. e6 (2022). doi:.
  • André Moraes Nicola, Jigar V Desai, Marc Swidergall, Muki Shey, Ivy M Dambuza. Immunological memory to fungal infections and vaccine development. 13:880037 (2022). doi:10.3389/fimmu.2022.880037/full.
  • Amy P Hsu, Agnieszka Korzeniowska, Cynthia C Aguilar, Jingwen Gu, Eric Karlins, Andrew J Oler, Gang Chen, Glennys V Reynoso, Joie Davis, Alexandria Chaput, Tao Peng, Ling Sun, Justin B Lack, Derek J Bays, Ethan R Stewart, Sarah E Waldman, Daniel A Powell, Fariba M Donovan, Jigar V Desai, Nima Pouladi, Debra A Long Priel, Daisuke Yamanaka, Sergio D Rosenzweig, Julie E Niemela, Jennifer Stoddard, Alexandra F Freeman, Christa S Zerbe, Douglas B Kuhns, Yves A Lussier, Kenneth N Olivier, Richard C Boucher, Heather D Hickman, Jeffrey Frelinger, Joshua Fierer, Lisa F Shubitz, Thomas L Leto, George R Thompson III, John N Galgiani, Michail S Lionakis, Steven M Holland. Immunogenetics associated with severe coccidioidomycosis. JCI insight 7(22):e159491 (2022). doi:.
  • Rebecca A Drummond, Jigar V Desai, Amy P Hsu, Vasileios Oikonomou, Donald C Vinh, Joshua A Acklin, Michael S Abers, Magdalena A Walkiewicz, Sarah L Anzick, Muthulekha Swamydas, Simon Vautier, Mukil Natarajan, Andrew J Oler, Daisuke Yamanaka, Katrin D Mayer-Barber, Yoichiro Iwakura, David Bianchi, Brian Driscoll, Ken Hauck, Ahnika Kline, Nicholas SP Viall, Christa S Zerbe, Elise MN Ferré, Monica M Schmitt, Tom DiMaggio, Stefania Pittaluga, John A Butman, Adrian M Zelazny, Yvonne R Shea, Cesar A Arias, Cameron Ashbaugh, Maryam Mahmood, Zelalem Temesgen, Alexander G Theofiles, Masayuki Nigo, Varsha Moudgal, Karen C Bloch, Sean G Kelly, M Suzanne Whitworth, Ganesh Rao, Cindy J Whitener, Neema Mafi, Juan Gea-Banacloche, Lawrence C Kenyon, William R Miller, Katia Boggian, Andrea Gilbert, Matthew Sincock, Alexandra F Freeman, John E Bennett, Rodrigo Hasbun, Constantinos M Mikelis, Kyung J Kwon-Chung, Yasmine Belkaid, Gordon D Brown, Jean K Lim, Douglas B Kuhns, Steven M Holland, Michail S Lionakis. Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis. The Journal of Clinical Investigation 132(22) (2022). doi:.
  • Jigar V Desai, Amanda Urban, Doris Z Swaim, Benjamin Colton, Lilian W Kibathi, Elise MN Ferrè, Pamela Stratton, Melissa A Merideth, Sally Hunsberger, Theresa Matkovits, Raphael Mannino, Steven M Holland, Edmund Tramont, Michail S Lionakis, Alexandra F Freeman. Efficacy of cochleated amphotericin B in mouse and human mucocutaneous candidiasis. Antimicrobial Agents and Chemotherapy 66(7):e00308-22 (2022). doi:10.1128/aac.00308-22.

2021

  • Timothy J Break, Vasileios Oikonomou, Nicolas Dutzan, Jigar V Desai, Marc Swidergall, Tilo Freiwald, Daniel Chauss, Oliver J Harrison, Julie Alejo, Drake W Williams, Stefania Pittaluga, Chyi-Chia R Lee, Nicolas Bouladoux, Muthulekha Swamydas, Kevin W Hoffman, Teresa Greenwell-Wild, Vincent M Bruno, Lindsey B Rosen, Wint Lwin, Andy Renteria, Sergio M Pontejo, John P Shannon, Ian A Myles, Peter Olbrich, Elise Ferre, Monica Schmitt, Daniel Martin, Daniel L Barber, Norma V Solis, Luigi D Notarangelo, David V Serreze, Mitsuru Matsumoto, Heather D Hickman, Philip M Murphy, Mark S Anderson, Jean K Lim, Steven M Holland, Scott G Filler, Behdad Afzali, Yasmine Belkaid, Niki M Moutsopoulos, Michail S Lionakis. Response to Comments on" Aberrant type 1 immunity drives susceptibility to mucosal fungal infections" COMMENT. SCIENCE 373(6561):1318-1318 (2021). doi:.
  • Timothy J Break, Vasileios Oikonomou, Nicolas Dutzan, Jigar V Desai, Marc Swidergall, Tilo Freiwald, Daniel Chauss, Oliver J Harrison, Julie Alejo, Drake W Williams, Stefania Pittaluga, Chyi-Chia R Lee, Nicolas Bouladoux, Muthulekha Swamydas, Kevin W Hoffman, Teresa Greenwell-Wild, Vincent M Bruno, Lindsey B Rosen, Wint Lwin, Andy Renteria, Sergio M Pontejo, John P Shannon, Ian A Myles, Peter Olbrich, Elise MN Ferré, Monica Schmitt, Daniel Martin, Genomics, Computational Biology Core 16, Daniel L Barber, Norma V Solis, Luigi D Notarangelo, David V Serreze, Mitsuru Matsumoto, Heather D Hickman, Philip M Murphy, Mark S Anderson, Jean K Lim, Steven M Holland, Scott G Filler, Behdad Afzali, Yasmine Belkaid, Niki M Moutsopoulos, Michail S Lionakis. Response to Comments on “Aberrant type 1 immunity drives susceptibility to mucosal fungal infections”. Science 373(6561):eabi8835 (2021). doi:10.1126/science.abi8835.
  • Evgeny Kiner, Elijah Willie, Brinda Vijaykumar, Kaitavjeet Chowdhary, Hugo Schmutz, Jodie Chandler, Alexandra Schnell, Pratiksha I Thakore, Graham LeGros, Sara Mostafavi, Diane Mathis, Christophe Benoist. Publisher Correction: Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes. Nature Immunology 22(5):666-668 (2021). doi:.
  • Ai Ing Lim, Taryn McFadden, Verena M Link, Seong-Ji Han, Rose-Marie Karlsson, Apollo Stacy, Taylor K Farley, Djalma S Lima-Junior, Oliver J Harrison, Jigar V Desai, Michail S Lionakis, Han-Yu Shih, Heather A Cameron, Yasmine Belkaid. Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring. Science 373(6558):eabf3002 (2021). doi:10.1126/science.abf3002.
  • Xin Huang, Charlotte Hurabielle, Rebecca A Drummond, Nicolas Bouladoux, Jigar V Desai, Choon K Sim, Yasmine Belkaid, Michail S Lionakis, Julia A Segre. Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies. Cell host & microbe 29(2):210-221. e6 (2021). doi:.
  • Nathalie Niyonzima, Jubayer Rahman, Natalia Kunz, Erin E West, Tilo Freiwald, Jigar V Desai, Nicolas S Merle, Alexandre Gidon, Bjørnar Sporsheim, Michail S Lionakis, Kristin Evensen, Beate Lindberg, Karolina Skagen, Mona Skjelland, Parul Singh, Markus Haug, Marieta M Ruseva, Martin Kolev, Jack Bibby, Olivia Marshall, Brett O’Brien, Nigel Deeks, Behdad Afzali, Richard J Clark, Trent M Woodruff, Milton Pryor, Zhi-Hong Yang, Alan T Remaley, Tom E Mollnes, Stephen M Hewitt, Bingyu Yan, Majid Kazemian, Máté G Kiss, Christoph J Binder, Bente Halvorsen, Terje Espevik, Claudia Kemper. Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation. Science immunology 6(66):eabf2489 (2021). doi:10.1126/sciimmunol.abf2489.
  • Michael S Abers, Ottavia M Delmonte, Emily E Ricotta, Jonathan Fintzi, Danielle L Fink, Adriana A Almeida de Jesus, Kol A Zarember, Sara Alehashemi, Vasileios Oikonomou, Jigar V Desai, Scott W Canna, Bita Shakoory, Kerry Dobbs, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Francesco Castelli, Camillo Rossi, Duilio Brugnoni, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio, Paolo Bonfanti, Riccardo Castagnoli, Daniela Montagna, Amelia Licari, Gian Luigi Marseglia, Emily F Gliniewicz, Elana Shaw, Dana E Kahle, Andre T Rastegar, Michael Stack, Katherine Myint-Hpu, Susan L Levinson, Mark J DiNubile, Daniel W Chertow, Peter D Burbelo, Jeffrey I Cohen, Katherine R Calvo, John S Tsang, Helen C Su, John I Gallin, Douglas B Kuhns, Raphaela Goldbach-Mansky, Michail S Lionakis, Luigi D Notarangelo, NIAID COVID-19 Consortium. An immune-based biomarker signature is associated with mortality in COVID-19 patients. JCI insight 6(1):e144455 (2021). doi:.
  • Timothy J Break, Vasileios Oikonomou, Nicolas Dutzan, Jigar V Desai, Marc Swidergall, Tilo Freiwald, Daniel Chauss, Oliver J Harrison, Julie Alejo, Drake W Williams, Stefania Pittaluga, Chyi-Chia R Lee, Nicolas Bouladoux, Muthulekha Swamydas, Kevin W Hoffman, Teresa Greenwell-Wild, Vincent M Bruno, Lindsey B Rosen, Wint Lwin, Andy Renteria, Sergio M Pontejo, John P Shannon, Ian A Myles, Peter Olbrich, Elise MN Ferré, Monica Schmitt, Daniel Martin, Genomics, Computational Biology Core 16, Daniel L Barber, Norma V Solis, Luigi D Notarangelo, David V Serreze, Mitsuru Matsumoto, Heather D Hickman, Philip M Murphy, Mark S Anderson, Jean K Lim, Steven M Holland, Scott G Filler, Behdad Afzali, Yasmine Belkaid, Niki M Moutsopoulos, Michail S Lionakis. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science 371(6526):eaay5731 (2021). doi:10.1126/science.aay5731.

2020

  • Marta Martin-Fernandez, María Bravo García-Morato, Conor Gruber, Sara Murias Loza, Muhammad Nasir Hayat Malik, Fahad Alsohime, Abdullah Alakeel, Rita Valdez, Sofija Buta, Guadalupe Buda, Marcelo A Marti, Margarita Larralde, Bertrand Boisson, Marta Feito Rodriguez, Xueer Qiu, Maya Chrabieh, Mohammed Al Ayed, Saleh Al Muhsen, Jigar V Desai, Elise MN Ferre, Sergio D Rosenzweig, Blanca Amador-Borrero, Luz Yadira Bravo-Gallego, Ruth Olmer, Sylvia Merkert, Montserrat Bret, Amika K Sood, Abdulkarim Al-Rabiaah, Mohamad Hani Temsah, Rabih Halwani, Michelle Hernandez, Frank Pessler, Jean-Laurent Casanova, Jacinta Bustamante, Michail S Lionakis, Dusan Bogunovic. Systemic type I IFN inflammation in human ISG15 deficiency leads to necrotizing skin lesions. Cell reports 31(6) (2020). doi:.
  • Chetan V Jawale, Kritika Ramani, De-dong Li, Bianca M Coleman, Rohan S Oberoi, Saran Kupul, Li Lin, Jigar V Desai, Greg M Delgoffe, Michail S Lionakis, Filitsa H Bender, Alexander J Prokopienko, Thomas D Nolin, Sarah L Gaffen, Partha S Biswas. Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease. Science translational medicine 12(548):eaay5691 (2020). doi:10.1126/scitranslmed.aay5691.
  • Anastasiia Gainullina, Li-Hao Huang, Helena Todorov, Kiwook Kim, Lim Sheau Yng, Andrew Kent, Baosen Jia, Kumba Seddu, Karen Krchma, Jun Wu, Karine Crozat, Elena Tomasello, Vipin Narang, Regine Dress, Peter See, Charlotte Scott, Sophie Gibbings, Geetika Bajpai, Jigar V Desai, Barbara Maier, Sébastien This, Peter Wang, Stephanie Vargas Aguilar, Lucie Poupel, Sébastien Dussaud, Tyng-An Zhou, Veronique Angeli, J Magarian Blander, Kyunghee Choi, Marc Dalod, Ivan Dzhagalov, Emmanuel L Gautier, Claudia Jakubzick, Kory Lavine, Michail S Lionakis, Helena Paidassi, Michael H Sieweke, Florent Ginhoux, Martin Guilliams, Christophe Benoist, Miriam Merad, Gwendalyn J Randolph, Alexey Sergushichev, Maxim N Artyomov, ImmGen Consortium. Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes. bioRxiv:2020.07. 15.204388 (2020). doi:10.1101/2020.07.15.204388.abstract.
  • Suk See De Ravin, Julie Brault, Ronald J Meis, Linhong Li, Narda Theobald, Aylin C Bonifacino, Hong Lei, Taylor Q Liu, Sherry Koontz, Cristina Corsino, Marissa A Zarakas, Jigar V Desai, Aaron B Clark, Uimook Choi, Mark E Metzger, Kamille West, Steven L Highfill, Elizabeth Kang, Douglas B Kuhns, Michail S Lionakis, David F Stroncek, Cynthia E Dunbar, John F Tisdale, Robert E Donahue, Gary A Dahl, Harry L Malech. NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease. Blood Advances 4(23):5976-5987 (2020). doi:.
  • Partha Sarathi Biswas, Chetan V Jawale, Kritika Ramani, Bianca Coleman, Rohan S Oberoi, Saran Kupul, Alexander J Prokopienko, Jigar V Desai, Greg M Delgoffe, Michail S Lionakis, Thomas D Nolin, Sarah L Gaffen. Metabolic ‘de-programming’of neutrophils protects against fatal bloodstream fungal infections during kidney disease. The Journal of Immunology 204(1_Supplement):82.35-82.35 (2020). doi:.
  • Mark Roschewski, Michail S Lionakis, Jeff P Sharman, Joseph Roswarski, Andre Goy, M Andrew Monticelli, Michael Roshon, Stephen H Wrzesinski, Jigar V Desai, Marissa A Zarakas, Jacob Collen, Keith M Rose, Ahmed Hamdy, Raquel Izumi, George W Wright, Kevin K Chung, Jose Baselga, Louis M Staudt, Wyndham H Wilson. Inhibition of Bruton tyrosine kinase in patients with severe COVID-19. Science immunology 5(48):eabd0110 (2020). doi:10.1126/sciimmunol.abd0110.
  • Stephanie Vargas Aguilar, Oscar Aguilar, Rhys Allan, El Ad David Amir, Veronique Angeli, Maxim N Artyomov, Natasha Asinovski, Jilian Astarita, K Frank Austen, Geetika Bajpai, Nora Barrett, Alev Baysoy, Christophe Benoist, Angelique Bellemare-Pelletier, Brad Berg, Adam Best, Natalie Bezman, David Blair, Julie M Blander, Milena Bogunovic, Patrick Brennan, Michael Brenner, Brian Brown, Matthew Buechler, Jason Buenrostro, Maria Acebes Casanova, Kyunghee Choi, Andrew Chow, Aleksey Chudnovskiy, Daniela Cipoletta, Nadia Cohen, James J Collins, Marco Colonna, Alison Cook, James Costello, Viviana Cremasco, Ty Crowl, Karine Crozat, Richard Cruse, June D'Angelo, Marc Dalod, Scott Davis, Cagatay Demiralp, Tianda Deng, Jigar V Desai, Fiona Desland, Maxime Dhainaut, Jiarui Ding, Andrew Doedens, Claudia Dominguez, Graeme Doran, Regine Dress, Michael Dustin, Daniel Dwyer, Ivan Dzhagalov, Kutlu Elpek, Ayla Ergun, Jeff Ericson, Eunice Esomonu, Keke Fairfax, Anne Fletcher, Michela Frascoli, Anja Fuchs, Anastasiia Gainullina, Shani Gal-Oz, Michael Gallagher, Emmanuel Gautier, Roi Gazit, Sophie Gibbings, Matthieu Giraud, Florent Ginhoux, Ananda Goldrath, Dagmar Gotthardt, Daniel Gray, Melanie Greter, Ricardo Grieshaber-Bouyer, Martin Guilliams, Sara Haidermota, Randy Hardy, Daigo Hashimoto, Julie Helft, Deborah Hendricks, Tracy Heng, Jonathan Hill, Gordon Hyatt. ImmGen at 15. Nature immunology 21(7):700-703 (2020). doi:.
  • Jigar V Desai, Amanda Urban, Doris Z Swaim, Elise Ferre, Benjamin Colton, Ruying Lu, Theresa Matkovits, Raphael J Mannino, Edmund Tramont, Michail Lionakis, Alexandra Freeman. 149. Efficacy of Cochleated Amphotericin B (CAMB) in Mouse and Human Mucocutaneous Candidiasis. Open Forum Infectious Diseases 7(Supplement_1):S204-S205 (2020). doi:.

2019

  • Jigar V Desai, Michail S Lionakis. Setting up home: fungal rules of commensalism in the mammalian gut. Cell host & microbe 25(3):347-349 (2019). doi:.
  • Chetan V Jawale, Kritika Ramani, Bianca M Coleman, Rohan S Oberoi, Saran Kupul, Alexander J Prokopienko, Jigar V Desai, Greg M Delgoffe, Michail S Lionakis, Thomas D Nolin, Sarah L Gaffen, Partha Sarathi Biswas. Metabolic ‘De-Programming’of Neutrophils Protects Against Fatal Bloodstream Fungal Infections in Kidney Disease. Available at SSRN 3403336 (2019). doi:.
  • Marissa A Zarakas, Jigar V Desai, Georgios Chamilos, Michail S Lionakis. Fungal infections with ibrutinib and other small-molecule kinase inhibitors. 13(3):86-98 (2019). doi:10.1007/s12281-019-00343-9.

2018

  • Timothy J Break, Jigar V Desai, Kelley R Healey, Mukil Natarajan, Elise MN Ferre, Christina Henderson, Adrian Zelazny, Ulrich Siebenlist, Christopher M Yates, Oren J Cohen, Robert J Schotzinger, David S Perlin, Edward P Garvey, Michail S Lionakis. VT-1598 inhibits the in vitro growth of mucosal Candida strains and protects against fluconazole-susceptible and-resistant oral candidiasis in IL-17 signalling-deficient mice. Journal of Antimicrobial Chemotherapy 73(8):2089-2094 (2018). doi:.
  • Timothy J Break, Jigar V Desai, Mukil Natarajan, Elise MN Ferre, Christina Henderson, Adrian M Zelazny, Ulrich Siebenlist, William J Hoekstra, Robert J Schotzinger, Edward P Garvey, Michail S Lionakis. VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans. Journal of Antimicrobial Chemotherapy 73(1):151-155 (2018). doi:.
  • Jigar V Desai, Frank L van de Veerdonk, Michail S Lionakis. Understanding the role of host immune responses in invasive candidiasis. Intensive care medicine 44(8):1310-1314 (2018). doi:10.1007/s00134-017-4988-5.
  • Jigar V Desai, Michail S Lionakis. The role of neutrophils in host defense against invasive fungal infections. 5(3):181-189 (2018). doi:10.1007/s40588-018-0098-6.
  • Katherine Lagree, Jigar V Desai, Jonathan S Finkel, Frederick Lanni. Microscopy of fungal biofilms. 43:100-107 (2018). doi:.
  • Loreto Abusleme, Patricia I Diaz, Alexandra F Freeman, Teresa Greenwell-Wild, Laurie Brenchley, Jigar V Desai, Weng-Ian Ng, Steven M Holland, Michail S Lionakis, Julia A Segre, Heidi H Kong, Niki M Moutsopoulos. Human defects in STAT3 promote oral mucosal fungal and bacterial dysbiosis. JCI insight 3(17):e122061 (2018). doi:.
  • Jigar V Desai. Candida albicans Hyphae: From Growth Initiation to Invasion. 4(1):10 (2018). doi:.
  • Mukil Natarajan, Amy P Hsu, Michael A Weinreich, Yuan Zhang, Julie E Niemela, John A Butman, Stefania Pittaluga, Janyce Sugui, Amanda L Collar, Jean K Lim, Tirdad Zangeneh, Tara Carr, Andrew J Oler, Morgan Similuk, Lindsey B Rosen, Jigar V Desai, Alexandra F Freeman, Steven M Holland, Kyung J Kwon-Chung, Joshua D Milner, Michail S Lionakis. Aspergillosis, eosinophilic esophagitis, and allergic rhinitis in signal transducer and activator of transcription 3 haploinsufficiency. Journal of Allergy and Clinical Immunology 142(3):993-997. e3 (2018). doi:.
  • Jigar V Desai, Ruying Lu, Alexandra F Freeman, Edmund Tramont, Jerry Jabbour, Raphael J Mannino, Michail S Lionakis. 370. Efficacy of Cochleated Amphotericin B (C-AMB) in Mouse Models of Oropharyngeal and Vulvovaginal Candidiasis. Open Forum Infectious Diseases 5(Suppl 1):S145 (2018). doi:.

2017

  • Timothy J Break, Jigar V Desai, Mukil Natarajan, Elise Ferre, Christina Henderson, Adrian M Zelazny, Christopher M Yates, Oren J Cohen, Robert J Schotzinger, Edward P Garvey, Michail Lionakis. VT-1598 Inhibits the in vitro Growth of Mucosal Candida Isolates and Protects Against Oropharyngeal Candidiasis in IL-17 Deficient Mice. Open Forum Infectious Diseases 4(suppl_1):S115-S115 (2017). doi:.
  • Anthony J St. Leger, Jigar V Desai, Rebecca Drummond, Abirami Kugadas, Fatimah Almaghrabi, Phyllis Silver, Mihaela Gadjeva, Yoichiro Iwakura, Michail S Lionakis, Rachel R Caspi. Microbiome-dependent modulation of mucosal immunity at the ocular surface.. The Journal of Immunology 198(Supplement_1):149.6-149.6 (2017). doi:.
  • Michail S Lionakis, Kieron Dunleavy, Mark Roschewski, Brigitte C Widemann, John A Butman, Roland Schmitz, Yandan Yang, Diane E Cole, Christopher Melani, Christine S Higham, Jigar V Desai, Michele Ceribelli, Lu Chen, Craig J Thomas, Richard F Little, Juan Gea-Banacloche, Sucharita Bhaumik, Maryalice Stetler-Stevenson, Stefania Pittaluga, Elaine S Jaffe, John Heiss, Nicole Lucas, Seth M Steinberg, Louis M Staudt, Wyndham H Wilson. Inhibition of B cell receptor signaling by ibrutinib in primary CNS lymphoma. Cancer cell 31(6):833-843. e5 (2017). doi:.
  • Jigar V Desai, Claudia Kemper, Jörg Köhl, Michail Lionakis. C5ar1-dependent phagocyte effector functions protect against systemic candidiasis. Open Forum Infectious Diseases 4:S115 (2017). doi:10.1093/ofid/ofx163.131.
  • Anthony J St Leger, Jigar V Desai, Rebecca A Drummond, Abirami Kugadas, Fatimah Almaghrabi, Phyllis Silver, Kumarkrishna Raychaudhuri, Mihaela Gadjeva, Yoichiro Iwakura, Michail S Lionakis, Rachel R Caspi. An ocular commensal protects against corneal infection by driving an interleukin-17 response from mucosal γδ T cells. Immunity 47(1):148-158. e5 (2017). doi:.
  • Anthony J St Leger, Jigar V Desai, Rebecca A Drummond, Abirami Kugadas, Fatimah Almaghrabi, Phyllis B Silver, Kumarkrishna Raychaudhuri, Mihaela Gadjeva, Yoichiro Iwakura, Michail S Lionakis, Rachel R Caspi. An eye commensal tunes the immune response at the ocular surface by eliciting IL-17 from mucosal γδ T cells: Mo-WS6-1. Cytokine 100:38-39 (2017). doi:.
  • Gennaro Roberto Abbamondi, El-Sayed Abdelwhab, Randy A Albrecht, Silvio Altarac, Rosa Araujo, John Atack, Alekos Athanasiadis, Nicholas Baird, Rossella Baldan, Françoise Van Bambeke, Tatiana Barichello, Emilie Bedard, Francesco Berti, Eugenia Bezirtzoglou, Patrick Blackall, Lucas Blanton, John Bowman, Randi H Brazeau, Jay Brown, Jeremy S Brown, Kevin Brulois, Vincent Bruno, Helen Y Buse, Sílvia Cervero Aragó, Thomas Chambers, Chieh-fu Chen, Myron Christodoulides, Simon Clarke, David Coleman, Jeroen Corver, Michał Czopowicz, Sana Dastgheyb, Sandip Datta, Astrid De Greeff, De La Gandara, Maria Pardos, Jigar Desai, Rod Devenish, Gill Diamond, Pierluigialdo Diciccio, Fernanda Domingues, Kelley Donham, Maura Donohue, Andrea Dowling, Elana Ehrlich, Ioannis Eleftherianos, Peter B Ernst, Manuel Espinosa-Urgel, Rong Fang, Lucía Fernández, Paul D Fey, Tomas Fiedler, Jaroslav Flegr, Stephan Forysthe, Timothy Foster, Pio Maria Furneri, Bianca Garner, Georg Baums, Christoph Giovanni, Gabriela Gherardi Godaly, Marisa Gómez, SM González Cappa, González Cappa, Marcelo Gottschalk, Sauli Haataja, Judith Hall, Hidekazu Hiroaki, Paul S Hoffman, Mark Holmes, Raquel Hontecillas-Magarzo, Bernhard Hube, Scott Hultgren, Matloob Husain, Peter J Irwin, Yoshihiro Izumiya, Ashvin R Jaiswal, Michele Jay-Russell, Shahid Karim, Rauni Kivistö. Acknowledgement to Reviewers of Pathogens in 2016. (2017). doi:.

2016

  • Jigar V Desai, Timothy J Break, Mukil Natarajan, Christina Henderson, Adrian M Zelazny, William J Hoekstra, Robert J Schotzinger, Edward P Garvey, Michail S Lionakis. VT-1129 and VT-1161 have in vitro activity against Candida isolates from patients with chronic mucocutaneous candidiasis. Open Forum Infectious Diseases 3(suppl_1):1635 (2016). doi:.
  • AJ St Leger, J Desai, R Drummond, F Almaghrabi, P Silver, M Lionakis, R Caspi. MICROBIOME-DEPENDENT MODULATION OF MUCOSAL IMMUNITY AT THE OCULAR SURFACE: O004. Cytokine 87:47-48 (2016). doi:.

2015

  • Jigar V Desai, Shaoji Cheng, Tammy Ying, M Hong Nguyen, Cornelius J Clancy, Frederick Lanni, Aaron P Mitchell. Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2. Pathogens 4(3):573-589 (2015). doi:.
  • Jigar V Desai, Aaron P Mitchell. Candida albicans Biofilm Development and Its Genetic Control. Microbial Biofilms:99-114 (2015). doi:10.1128/9781555817466.ch5.

2014

  • Jigar V Desai, Aaron P Mitchell, David R Andes. Fungal biofilms, drug resistance, and recurrent infection. 4(10):a019729 (2014). doi:.

2013

  • Jigar V Desai, Vincent M Bruno, Shantanu Ganguly, Ronald J Stamper, Kaitlin F Mitchell, Norma Solis, Elizabeth M Hill, Wenjie Xu, Scott G Filler, David R Andes, Saranna Fanning, Frederick Lanni, Aaron P Mitchell. Regulatory role of glycerol in Candida albicans biofilm formation. MBio 4(2):10.1128/mbio. 00637-12 (2013). doi:10.1128/mbio.00637-12.

2012

  • Mohini S Ghatge, Roberto Contestabile, Martino L di Salvo, Jigar V Desai, Amit K Gandhi, Christina M Camara, Rita Florio, Isabel N González, Alessia Parroni, Verne Schirch, Martin K Safo. Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase. 7(7):e41680 (2012). doi:10.1371/journal.pone.0041680.
  • Jonathan S Finkel, Wenjie Xu, David Huang, Elizabeth M Hill, Jigar V Desai, Carol A Woolford, Jeniel E Nett, Heather Taff, Carmelle T Norice, David R Andes, Frederick Lanni, Aaron P Mitchell. Portrait of Candida albicans Adherence Regulators. PLoS pathogens 8(2):e1002525 (2012). doi:10.1371/journal.ppat.1002525.
  • Amit K Gandhi, Jigar V Desai, Mohini S Ghatge, Martino L di Salvo, Stefano Di Biase, Richmond Danso-Danquah, Faik N Musayev, Roberto Contestabile, Verne Schirch, Martin K Safo. Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. PLoS One 7(7):e40954 (2012). doi:10.1371/journal.pone.0040954.
  • Shoba Subramanian, Carol A Woolford, Jigar V Desai, Frederick Lanni, Aaron P Mitchell. cis- and trans-Acting Localization Determinants of pH Response Regulator Rim13 in Saccharomyces cerevisiae. Eukaryotic Cell 11(10):1201-1209 (2012). doi:10.1128/ec.00158-12.

2010

  • Jigarkumar Desai. Pyridoxal Kinase: Its Role in Vitamin B6 Metabolism. (2010). doi:.